A new class of ferrocenyl surfactants based on covalent linkage between amino acids or peptides and ferrocene was designed. Accordingly, five ferrocenyl amphiphiles, FcS1–5, were synthesized, and their aggregation behaviors in aqueous solutions were studied. Compared to the other surfactants containing ferrocenyl units, FcS have a relatively smaller size and low molecular weight and are easy to synthesize. The influences of the number of carboxylic acid head groups and the number of Fc group in the hydrophobic tail, on the stability and aggregation behavior of these amphiphiles in aqueous medium, were explored to deduce the structure property relationships. A combination of fluorescence and dynamic light scattering techniques was used to elucidate the behavior of these molecules. A good agreement between the results obtained using different techniques was observed.

中文翻译：

---

二茂铁与氨基酸和肽的两亲共轭物：设计、合成和研究它们的聚集行为

设计了一类基于氨基酸或肽与二茂铁之间共价键的新型二茂铁表面活性剂。因此，五个二茂铁基两亲物FcS1–5, 合成，并研究了它们在水溶液中的聚集行为。与其他含有二茂铁基单元的表面活性剂相比，FcS具有相对较小的尺寸和较低的分子量，并且易于合成。探讨了羧酸头部基团数量和疏水尾部Fc基团数量对这些两亲物在水性介质中的稳定性和聚集行为的影响，以推导出结构性质关系。结合使用荧光和动态光散射技术来阐明这些分子的行为。观察到使用不同技术获得的结果之间有很好的一致性。