Fibrinolysis is of paramount importance in maintaining or regaining the patency of veins and pulmonary arteries obstructed by thrombi. Growing experimental and clinical evidence indicates that impaired fibrinolysis mediated by multiple complex mechanisms is involved in venous thromboembolism (VTE). Global plasma fibrin clot lysis markers, especially clot lysis time, have been reported to predict recurrent deep-vein thrombosis and pulmonary embolism. The current overview summarizes available data linking fibrinolysis to VTE and its long-term sequelae.

中文翻译：

---

静脉血栓栓塞症中的纤溶

纤溶对于维持或恢复被血栓阻塞的静脉和肺动脉的通畅至关重要。越来越多的实验和临床证据表明，由多种复杂机制介导的纤溶受损与静脉血栓栓塞 (VTE) 相关。据报道，全球血浆纤维蛋白凝块溶解标志物，尤其是凝块溶解时间，可预测复发性深静脉血栓形成和肺栓塞。当前概述总结了将纤溶与 VTE 及其长期后遗症联系起来的可用数据。