ABSTRACT

Introduction: Gallbladder carcinosarcoma (GBCS) is a rare neoplasm, and previous studies regarding to GBCS were case reports/case series, absence of large retrospective analyses, or systemic review. This review summarizes the current literature on accurate information of GBCS to assist clinicians to accurately diagnose and treat this malignancy.

Areas covered: The authors retrieved relevant documents of GBCS from PubMed and Medline. This review elaborates on the knowledge of GBCS covering epidemiology, potential mechanism, clinical manifestation, diagnosis, treatment, and prognosis.

Expert opinion: The majority of GBCS patients are easily misdiagnosed as GBC and usually treated as GBC. However, the biological behavior and outcome of GBCS is different from that of GBC. GBCS should be considered as a separate disease.

摘要

简介: 胆囊癌肉瘤 (GBCS) 是一种罕见的肿瘤，以前关于 GBCS 的研究是病例报告/病例系列，缺乏大型回顾性分析或系统评价。本综述总结了当前关于GBCS准确信息的文献，以帮助临床医生准确诊断和治疗这种恶性肿瘤。

涵盖领域：作者从 PubMed 和 Medline 检索了 GBCS 的相关文件。本综述从流行病学、潜在机制、临床表现、诊断、治疗和预后等方面阐述了GBCS的相关知识。

专家意见：大部分GBCS患者容易误诊为GBC，通常按GBC治疗。然而，GBCS 的生物学行为和结果与 GBC 不同。GBCS 应被视为一种单独的疾病。