Poor health and low cardiorespiratory fitness (CRF) contribute substantially to the shortened lifespan of individuals with schizophrenia spectrum disorders (SSDs). Increasing physical activity has demonstrated value; however, there are limited interventions that are accessible and adequately address motivational challenges. This paper reports on an open trial of Physical Activity Can Enhance Life (PACE-Life), a motivational theory-based manualized multicomponent walking intervention. The primary aim was to examine the feasibility of implementing PACE-Life through meeting the recruitment target (n = 14), attendance and adherence rates, and participant feedback. The secondary aim was to assess the impact of PACE-Life on intermediate targets (autonomous motivation and satisfaction of autonomy, relatedness, and competence needs), proximal outcomes (Fitbit steps/day and minutes spent walking), the primary outcome (CRF), and secondary outcomes (loneliness, symptoms, resting heart rate, blood pressure, weight, body mass index, and hip and waist circumference). Seventeen participants with SSDs enrolled in a 24-week open trial. Assessments occurred at baseline, mid-point, post-test, and one-month follow-up. The recruitment target was exceeded, the group attendance rate was 34%, Fitbit adherence rate was 54%, and participant feedback indicated satisfaction with the intervention as well as a positive group environment. There was a large improvement in the primary outcome of CRF with 77% of participants achieving clinically significant improvement at post-test. Small and medium effect size increases were observed in autonomous motivation and satisfaction of autonomy, relatedness, and competence needs. Fitbit data and secondary outcomes generally remained unchanged or worsened during the intervention. Results from this open trial indicate that PACE-Life leads to meaningful changes in CRF among people with SSDs.

健康状况不佳和心肺健康 (CRF) 低下会大大缩短精神分裂症谱系障碍 (SSD) 患者的寿命。增加身体活动已证明其价值；然而，能够获得并充分解决激励挑战的干预措施有限。本文报道了一项体育活动可以改善生活 (PACE-Life) 的公开试验，这是一种基于动机理论的手动多组分步行干预。主要目的是通过满足招募目标（n = 14）、出勤率和坚持率以及参与者反馈来检查实施 PACE-Life 的可行性。次要目标是评估 PACE-Life 对中间目标（自主动机和对自主、相关性和能力需求的满足）的影响，近端结果（Fitbit 步数/天和步行分钟数）、主要结果 (CRF) 和次要结果（孤独感、症状、静息心率、血压、体重、体重指数以及臀部和腰围）。十七名使用 SSD 的参与者参加了为期 24 周的公开试验。评估发生在基线、中点、测试后和一个月的随访中。超过了招募目标，小组出勤率为 34%，Fitbit 依从率为 54%，参与者反馈对干预表示满意以及积极的小组环境。CRF 的主要结果有很大改善，77% 的参与者在测试后实现了临床显着改善。在自主动机和自主满意度、相关性、和能力需求。Fitbit 数据和次要结果在干预期间通常保持不变或恶化。这项公开试验的结果表明，PACE-Life 会导致 SSD 患者的 CRF 发生有意义的变化。