Severe cutaneous adverse drug reactions (SCARs) are rare but deadly drug reactions with severe damages to patients. One of the most well-known SCARs risk factors is the human leukocyte antigen (HLA) genes polymorphism. Among the HLA polymorphic alleles, the HLA-A*33:03 allele has been found in association with SCARs induced by various drugs, especially in Asian people. There has not been any report on the specific detection protocol of the HLA-A*33:03 allele.

中文翻译：

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一种新颖的嵌套等位基因特异性PCR方案，用于检测越南人中与SCAR相关的等位基因HLA-A * 33：03。

严重的皮肤不良药物反应（SCAR）很少见，但致命的药物反应会对患者造成严重损害。SCAR最著名的危险因素之一是人白细胞抗原（HLA）基因多态性。在HLA多态性等位基因中，已发现HLA-A * 33：03等位基因与各种药物诱导的SCAR相关，特别是在亚洲人中。尚未有关于HLA-A * 33：03等位基因特定检测方案的报告。