The development of a painless, non-invasive, and faster way to diabetic wound healing is at the forefront of research. The complexity associated with diabetic wounds makes it a cause for concern amongst diabetic patients and the world at large. Irradiation of cells generates a photobiomodulatory response on cells and tissues, directly causing alteration of cellular processes and inducing diabetic wound repair. Photobiomodulation therapy (PBMT) using red and near-infrared (NIR) wavelengths is being considered as a promising technique for speeding up the rate of diabetic wound healing, eradication of pain and reduction of inflammation through the alteration of diverse cellular and molecular processes. This review presents the extent to which the potential of red and NIR wavelengths have been harnessed in PBMT for diabetic wound healing. Important research challenges and gaps are identified and discussed, and future directions mapped out. This review thus provides useful insights and strategies into improvement of PBMT, including its acceptance within the global medical research community.

中文翻译：

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糖尿病伤口愈合中的光生物调节：红光和近红外波长应用综述

开发一种无痛、无创且更快的糖尿病伤口愈合方法处于研究的前沿。与糖尿病伤口相关的复杂性使其成为糖尿病患者和整个世界关注的一个原因。细胞的辐照对细胞和组织产生光生物调节反应，直接引起细胞过程的改变并诱导糖尿病伤口修复。使用红色和近红外 (NIR) 波长的光生物调节疗法 (PBMT) 被认为是一种很有前途的技术，可通过改变多种细胞和分子过程来加快糖尿病伤口愈合、消除疼痛和减少炎症的速度。本综述介绍了红光和 NIR 波长在 PBMT 中用于糖尿病伤口愈合的潜力的程度。确定和讨论了重要的研究挑战和差距，并规划了未来的方向。因此，本综述为改善 PBMT 提供了有用的见解和策略，包括其在全球医学研究界的接受程度。