The impact of the observed sea surface temperature (SST) frequency in the model initialization on the prediction of the boreal summer intraseasonal oscillation (BSISO) over the Western North Pacific (WNP) is investigated using the Beijing Climate Center Climate System Model. Three sets of hindcast experiments initialized by the observed monthly, weekly and daily SST data (referred to as the Exp_MSST, Exp_WSST and Exp_DSST, respectively) are conducted with 3-month integration starting from the 1st, 11th, and 21st day of each month in June–August during 2000–2014, respectively. The results show that the useful prediction skill of BSISO index reaches out to about 10 days in the Exp_MSST, and further increases by 1–2 days in the Exp_WSST and Exp_DSST. The skill differences among various hindcast experiments are especially apparent during the forecast time of 6–20 days. Focusing on the strong BSISO cases in this period, the BSISO activity and its related moist static energy (MSE) characteristics over the WNP are further diagnosed. It is found that from the Exp_MSST to the Exp_WSST and Exp_DSST, the enhanced BSISO prediction skill is associated with the more realistic variations of intraseasonal MSE and its tendency. Among the various budget terms that dominate the MSE tendency, the surface latent heat flux and MSE advection are evidently improved, with reduction of mean biases by more than 21% and 10%, respectively. Therefore, the better reproduced MSE variation may contribute to the more skillful BSISO forecast through improving the surface evaporation as well as atmospheric convergence and divergence that related to the BSISO activity. Our findings suggest the necessity of increasing the observed SST frequency (i.e., from monthly to weekly or daily) in the initialization process of coupled models to enhance the actual BSISO predictability, since some current subseasonal forecast operations and researches still use relatively low-frequency SST observations for the model initialization.