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Characterization of Age and Polarity at Onset in Bipolar Disorder
medRxiv - Psychiatry and Clinical Psychology Pub Date : 2021-04-16 , DOI: 10.1101/2021.04.16.21251163 Janos L. Kalman , Loes M. Olde Loohuis , Annabel Vreeker , Andrew McQuillin , Eli A. Stahl , Douglas Ruderfer , Maria Grigoroiu-Serbanescu , Georgia Panagiotaropoulou , Stephan Ripke , Tim B Bigdeli , Frederike Stein , Tina Meller , Susanne Meinert , Helena Pelin , Fabian Streit , Sergi Papiol , Mark J Adams , Rolf Adolfsson , Kristina Adorjan , Ingrid Agartz , Sofie R. Aminoff , Heike Anderson-Schmidt , Ole A. Andreassen , Raffaella Ardau , Jean-Michel Aubry , Ceylan Balaban , Nicholas Bass , Bernhard T Baune , Frank Bellivier , Antonio Benabarre , Susanne Bengesser , Wade H Berrettini , Marco P. Boks , Evelyn J Bromet , Katharina Brosch , Monika Budde , William Byerley , Pablo Cervantes , Catina Chillotti , Sven Cichon , Scott R Clark , Ashley L. Comes , Aiden Corvin , William Coryell , Nick Craddock , David W. Craig , Paul E. Croarkin , Cristiana Cruceanu , Piotr M. Czerski , Nina Dalkner , Udo Dannlowski , Franziska Degenhardt , J. Raymond DePaulo , Srdjan Djurovic , Howard J. Edenberg , Mariam Al Eissa , Torbjørn Elvsåshagen , Bruno Etain , Ayman H Fanous , Frederike Fellendorf , Alessia Fiorentino , Andreas J Forstner , Mark A. Frye , Janice M. Fullerton , Katrin Gade , Julie Garnham , Kirov George , Elliot Gershon , Michael Gill , Fernando S. Goes , Katherine Gordon-Smith , Paul Grof , Jose Guzman-Parra , Tim Hahn , Maria Hake , Roland Hasler , Urs Heilbronner , Stephane Jamain , Esther Jimenez , Ian Jones , Lisa Jones , Lina Jonsson , Rene S Kahn , John R. Kelsoe , James L. Kennedy , Tilo Kircher , Sarah Kittel-Schneider , Farah Klöhn-Saghatolislam , James A Knowles , Thorsten Manfred Kranz , Trine Vik Lagerberg , Mikael Landen , William B Lawson , Marion Leboyer , Qingqin S Li , Mario Maj , Dolores Malaspina , Mirko Manchia , Fermin Mayoral , Susan L McElroy , Melvin G McInnis , Andrew M McIntosh , Helena Medeiros , Ingrid Melle , Vihra Milanova , Philip B. Mitchell , Palmiero Monteleone , Alessio Maria Monteleone , Markus M Nöthen , Tomas Novak , John J Nurnberger , Niamh O’Brien , Kevin S. O’Connell , Claire O’Donovan , Michael C O’Donovan , Nils Opel , Abigail Ortiz , Michael J Owen , Erik Pålsson , Carlos Pato , Michele T Pato , Joanna Pawlak , Julia-Katharina Pfarr , Claudia Pisanu , James B. Potash , Mark H Rapaport , Daniela Reich-Erkelenz , Andreas Reif , Eva Reininghaus , Jonathan Repple , Helène Richard-Lepouriel , Marcella Rietschel , Kai Ringwald , Gloria Roberts , Guy Rouleau , Sabrina Schaupp , William A Scheftner , Simon Schmitt , Peter R. Schofield , K Oliver Schubert , Eva C. Schulte , Barbara Schweizer , Fanny Senner , Giovanni Severino , Sally Sharp , Claire Slaney , Olav B. Smeland , Janet L Sobell , Alessio Squassina , Pavla Stopkova , John Strauss , Alfonso Tortorella , Gustavo Turecki , Joanna Twarowska-Hauser , Marin Veldic , Eduard Vieta , John B. Vincent , Wei Xu , Clement C. Zai , Peter P. Zandi , Maria Del Zompo , Arianna Di Florio , Jordan W. Smoller , Joanna M. Biernacka , Francis J. McMahon , Martin Alda , Bertram Muller-Myhsok , Nikolaos Koutsouleris , Peter Falkai , Nelson B. Freimer , Till F.M. Andlauer , Thomas G Schulze , Roel A. Ophoff , , ,
medRxiv - Psychiatry and Clinical Psychology Pub Date : 2021-04-16 , DOI: 10.1101/2021.04.16.21251163 Janos L. Kalman , Loes M. Olde Loohuis , Annabel Vreeker , Andrew McQuillin , Eli A. Stahl , Douglas Ruderfer , Maria Grigoroiu-Serbanescu , Georgia Panagiotaropoulou , Stephan Ripke , Tim B Bigdeli , Frederike Stein , Tina Meller , Susanne Meinert , Helena Pelin , Fabian Streit , Sergi Papiol , Mark J Adams , Rolf Adolfsson , Kristina Adorjan , Ingrid Agartz , Sofie R. Aminoff , Heike Anderson-Schmidt , Ole A. Andreassen , Raffaella Ardau , Jean-Michel Aubry , Ceylan Balaban , Nicholas Bass , Bernhard T Baune , Frank Bellivier , Antonio Benabarre , Susanne Bengesser , Wade H Berrettini , Marco P. Boks , Evelyn J Bromet , Katharina Brosch , Monika Budde , William Byerley , Pablo Cervantes , Catina Chillotti , Sven Cichon , Scott R Clark , Ashley L. Comes , Aiden Corvin , William Coryell , Nick Craddock , David W. Craig , Paul E. Croarkin , Cristiana Cruceanu , Piotr M. Czerski , Nina Dalkner , Udo Dannlowski , Franziska Degenhardt , J. Raymond DePaulo , Srdjan Djurovic , Howard J. Edenberg , Mariam Al Eissa , Torbjørn Elvsåshagen , Bruno Etain , Ayman H Fanous , Frederike Fellendorf , Alessia Fiorentino , Andreas J Forstner , Mark A. Frye , Janice M. Fullerton , Katrin Gade , Julie Garnham , Kirov George , Elliot Gershon , Michael Gill , Fernando S. Goes , Katherine Gordon-Smith , Paul Grof , Jose Guzman-Parra , Tim Hahn , Maria Hake , Roland Hasler , Urs Heilbronner , Stephane Jamain , Esther Jimenez , Ian Jones , Lisa Jones , Lina Jonsson , Rene S Kahn , John R. Kelsoe , James L. Kennedy , Tilo Kircher , Sarah Kittel-Schneider , Farah Klöhn-Saghatolislam , James A Knowles , Thorsten Manfred Kranz , Trine Vik Lagerberg , Mikael Landen , William B Lawson , Marion Leboyer , Qingqin S Li , Mario Maj , Dolores Malaspina , Mirko Manchia , Fermin Mayoral , Susan L McElroy , Melvin G McInnis , Andrew M McIntosh , Helena Medeiros , Ingrid Melle , Vihra Milanova , Philip B. Mitchell , Palmiero Monteleone , Alessio Maria Monteleone , Markus M Nöthen , Tomas Novak , John J Nurnberger , Niamh O’Brien , Kevin S. O’Connell , Claire O’Donovan , Michael C O’Donovan , Nils Opel , Abigail Ortiz , Michael J Owen , Erik Pålsson , Carlos Pato , Michele T Pato , Joanna Pawlak , Julia-Katharina Pfarr , Claudia Pisanu , James B. Potash , Mark H Rapaport , Daniela Reich-Erkelenz , Andreas Reif , Eva Reininghaus , Jonathan Repple , Helène Richard-Lepouriel , Marcella Rietschel , Kai Ringwald , Gloria Roberts , Guy Rouleau , Sabrina Schaupp , William A Scheftner , Simon Schmitt , Peter R. Schofield , K Oliver Schubert , Eva C. Schulte , Barbara Schweizer , Fanny Senner , Giovanni Severino , Sally Sharp , Claire Slaney , Olav B. Smeland , Janet L Sobell , Alessio Squassina , Pavla Stopkova , John Strauss , Alfonso Tortorella , Gustavo Turecki , Joanna Twarowska-Hauser , Marin Veldic , Eduard Vieta , John B. Vincent , Wei Xu , Clement C. Zai , Peter P. Zandi , Maria Del Zompo , Arianna Di Florio , Jordan W. Smoller , Joanna M. Biernacka , Francis J. McMahon , Martin Alda , Bertram Muller-Myhsok , Nikolaos Koutsouleris , Peter Falkai , Nelson B. Freimer , Till F.M. Andlauer , Thomas G Schulze , Roel A. Ophoff , , ,
Background Studying the phenotypic and genetic characteristics of age and polarity at onset (AAO, PAO) in bipolar disorder (BD) can provide new insights into disease pathology and facilitate the development of screening tools.
中文翻译：
双相情感障碍发作时年龄和极性的特征
背景研究双相情感障碍（BD）发病年龄和极性（AAO，PAO）的表型和遗传特征可以为疾病病理学提供新见解，并有助于开发筛查工具。
更新日期：2021-04-18
中文翻译：
双相情感障碍发作时年龄和极性的特征
背景研究双相情感障碍（BD）发病年龄和极性（AAO，PAO）的表型和遗传特征可以为疾病病理学提供新见解，并有助于开发筛查工具。
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