Tyrosinase is a copper-containing enzyme involved in the biosynthesis of melanin pigment, which is the most important photo protective agent against skin photo carcinogenesis. Excess production of melanin causes hyperpigmentation leading to undesired browning in human skin, fruits, and vegetable as well as plant-derived foods. Moreover, the role of tyrosinase in the onset and progression of various diseases such as cancers, Alzheimer's, and Parkinson diseases has been well documented in the literature. In this respect, tyrosinase inhibitors have been in the center of attention particularly as the efficient skin whitening agents. Among a wide range of compounds possessing anti-tyrosinase activity, peptides both natural and synthetic derivatives have attracted attention due to high potency and safety.

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天然和合成肽：有效的酪氨酸酶抑制剂

酪氨酸酶是一种参与黑色素生物合成的含铜酶，黑色素是防止皮肤光致癌的最重要的光保护剂。黑色素的过量产生会导致色素沉着过度，从而导致人体皮肤、水果和蔬菜以及植物性食物出现不希望的褐变。此外，酪氨酸酶在各种疾病（如癌症、阿尔茨海默病和帕金森病）的发生和发展中的作用已在文献中得到充分证明。在这方面，酪氨酸酶抑制剂尤其作为有效的皮肤增白剂已成为关注的焦点。在具有抗酪氨酸酶活性的多种化合物中，天然和合成衍生物的肽因其高效能和安全性而受到关注。