Background

We sought to estimate the prevalence of diabetes mellitus (DM) and pre-DM and their associated factors among a sample of the Iranian urban population between 2017 and 2019.

Methods

The present investigation is a sub-study on the HAMRAH cohort study, a longitudinal population-based cohort study to assess the 10-year risk of cardiovascular diseases and their related risk factors in the adult population of the Iranian capital, Tehran. Via a multistage cluster randomized sampling method, 2123 adults aged between 30 and 75 years who had no history of cardiovascular diseases were selected for the study. With the aid of the 2010 American Diabetes Association criteria for the definition of DM and pre-DM, age and sex-specific prevalence rates were estimated.

Results

The estimated overall prevalence of DM was 14.3% (95% CI: 13.1%–15.8%): 10.4% known DM (95% CI: 9.1%–11.8%) and 4% newly diagnosed DM (95% CI: 3.1%–5.1%). Pre-DM was detected in about 29.2% of the study participants (95% CI: 22.9–36.3%). Our logistic regression analysis revealed that increasing age, higher systolic blood pressure, higher levels of triglycerides, and lower levels of high-density lipoprotein were significantly associated with DM.

Conclusions

DM and pre-DM follow a notable incremental pattern among the Iranian urban population. This finding underscores the significance of the need to improve prevention and screening strategies in the Iranian urban population.

中文翻译：

---

现代伊朗城市人口糖尿病前期患病率升高的警告信号

背景

我们试图估计 2017 年至 2019 年伊朗城市人口样本中糖尿病 (DM) 和糖尿病前期的患病率及其相关因素。

方法

本调查是 HAMRAH 队列研究的子研究，该研究是一项基于人群的纵向队列研究，旨在评估伊朗首都德黑兰成年人群中心血管疾病的 10 年风险及其相关风险因素。通过多阶段整群随机抽样方法，选择了 2123 名年龄在 30 至 75 岁之间且没有心血管疾病史的成年人进行研究。借助 2010 年美国糖尿病协会定义 DM 和糖尿病前期的标准，估计了年龄和性别特定的患病率。

结果

DM 的估计总体患病率为 14.3%（95% CI：13.1%–15.8%）：10.4% 已知 DM（95% CI：9.1%–11.8%）和 4% 新诊断的 DM（95% CI：3.1%– 5.1%）。在大约 29.2% 的研究参与者中检测到了糖尿病前期（95% CI：22.9-36.3%）。我们的逻辑回归分析显示，年龄增加、收缩压升高、甘油三酯水平升高和高密度脂蛋白水平降低与 DM 显着相关。

结论

DM 和前 DM 在伊朗城市人口中遵循显着的增量模式。这一发现强调了改进伊朗城市人口预防和筛查策略的重要性。