Tuberculosis remains a worldwide problem fueled by the HIV epidemic. TB infection impacts HIV progression and mortality even with treatment. Egypt has increasing HIV prevalence, although still in low prevalent areas. Urinary LAM was positive in 22 (95.7%) of TB patients and 1 (1.9%) of non TB group. Sensitivity was 95.7%, specificity 98.1%, positive and negative predictive values were 95.7% and 98.1% respectively, with accuracy 97.4%. Urinary LAM ELISA assay has the highest sensitivity (95.7%) in relation to other tests used for TB detection in HIV patients and its concentration was highly correlated to CD4 cell count and the extent of radiological changes. The use of urinary LAM in HIV patients is rapid, safe, available, and helpful tool for ruling in TB especially for those who cannot expectorate, critically ill, with low CD4, or presented by multiple system affection.

中文翻译：

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尿液中脂质arabinomannanan（LAM）的检测在艾滋病毒患者肺结核诊断中的作用：埃及经验

结核病仍然是艾滋病毒流行的全球性问题。结核病感染即使经过治疗也会影响艾滋病毒的进展和死亡率。埃及的艾滋病毒流行率不断上升，尽管仍处于低流行地区。结核病患者中22例（95.7％）尿LAM阳性，非结核病组1例（1.9％）尿LAM阳性。敏感性为95.7％，特异性为98.1％，阳性和阴性预测值分别为95.7％和98.1％，准确度为97.4％。相对于在HIV患者中用于TB检测的其他检测，尿液LAM ELISA检测具有最高的灵敏度（95.7％），并且其浓度与CD4细胞计数和放射学改变的程度高度相关。在HIV患者中使用尿液LAM是快速，安全，可用且有用的结核病诊断工具，特别是对于那些无法排尿，重症，CD4较低的人，