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Evidence for role of capillaries in regulation of skeletal muscle oxygen supply
Microcirculation ( IF 2.4 ) Pub Date : 2021-04-14 , DOI: 10.1111/micc.12699
Nour W Ghonaim 1 , Graham M Fraser 2 , Daniel Goldman 1, 3 , Stephanie Milkovich 3, 4 , Jun Yang 1, 5 , Christopher G Ellis 1, 3, 4
Affiliation  

How oxygen (O2) supply to capillaries is regulated to match the tissue's demand is unknown. Erythrocytes have been proposed as sensors in this regulatory mechanism since they release ATP, a vasodilator, in an oxygen saturation (SO2)-dependent manner. ATP causes hyperpolarization of endothelial cells resulting in conducted vasodilation to arterioles.

中文翻译:

毛细血管在调节骨骼肌供氧中的作用的证据

如何调节毛细血管的氧气 (O 2 ) 供应以匹配组织的需求尚不清楚。由于红细胞以氧饱和度 (SO 2 ) 依赖性方式释放血管扩张剂 ATP,因此已提出红细胞作为该调节机制中的传感器。ATP 引起内皮细胞的超极化,导致对小动脉进行血管舒张。
更新日期:2021-04-14
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