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Successful Treatment of Late Isolated Bone Metastasis in a Patient with Bilateral Retinoblastoma Using an Unconventional Method
Ocular Oncology and Pathology Pub Date : 2021-04-14 , DOI: 10.1159/000514620
Deepthi Boddu 1 , Priyakumari Thankamony 1 , Reshma Prakasam 2 , Subin Sugath 3 , Aswin Kumar 4 , Sindhu Nair 5
Affiliation  

Though survival in bilateral retinoblastoma (RB) has improved due to advancement in diagnostics and treatment modalities, children require long-term follow-ups for recurrence and second malignancies. We report a case of bilateral RB in a 7-month-old baby who was treated with chemotherapy, transpupillary thermotherapy, and periocular carboplatin for both eyes following which there was complete regression of tumour. Six and a half years after treatment, the child presented with metastatic recurrence of tumour in the left ulna. He was treated successfully with chemotherapy, extracorporeal radiation and reimplantation therapy. A less aggressive treatment approach for isolated bone relapse may be considered in selected cases.
Ocul Oncol Pathol


中文翻译:

使用非常规方法成功治疗双侧视网膜母细胞瘤患者的晚期孤立性骨转移

尽管由于诊断和治疗方式的进步,双侧视网膜母细胞瘤(RB)的生存率有所提高,但儿童仍需要对复发和第二恶性肿瘤进行长期随访。我们报道了一名 7 个月大婴儿的双侧 RB 病例,该婴儿接受化疗、瞳孔温热疗法和双眼眼周卡铂治疗,随后肿瘤完全消退。治疗六年半后,孩子出现左尺骨肿瘤转移性复发。通过化疗、体外放射和再植入治疗,他得到了成功的治疗。在某些情况下,可以考虑采用不太积极的治疗方法来治疗孤立性骨复发。
眼肿瘤病理
更新日期:2021-04-14
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