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COVID-19 and mortality risk in patients with psychiatric disorders
medRxiv - Psychiatry and Clinical Psychology Pub Date : 2021-04-13 , DOI: 10.1101/2021.04.08.21255046
George Kirov , Emily Baker

COVID-19 has already caused the deaths of over 2.5 million people worldwide. Patients with certain medical conditions and severe psychiatric disorders are at increased risk of dying from it. However, such people have a reduced life expectancy anyway, raising the question whether COVID-19 incurs a specific risk for such patients for dying, over and above the risk of dying from other causes. We analysed the UK Biobank data of half a million middle-aged participants from the UK. From the start of 2020 up to 24th January 2021, 894 participants had died from COVID-19 and another 4,562 had died from other causes. We demonstrate that the risk of dying from COVID-19 among patients with mental health problems, especially those with dementia, schizophrenia, or bipolar disorder, is increased compared to the risk of dying from other causes. This increase among patients with severe psychiatric disorders cannot be explained solely by the higher rate of diabetes or cardiovascular disorders.

中文翻译:

精神疾病患者的COVID-19和死亡风险

COVID-19已在全球造成250万人死亡。患有某些疾病和严重精神病的患者死亡的风险更高。但是,无论如何,这类人的预期寿命都降低了,这就提出了一个问题,即COVID-19是否会给这类患者带来特殊的死亡风险,而不是其他原因导致的死亡风险。我们分析了英国半数参与者的英国生物库数据。从2020年初到2021年1月24日,有894名参与者死于COVID-19,另有4,562名参与者死于其他原因。我们证明,与其他原因导致的死亡风险相比,患有精神健康问题的患者(尤其是患有痴呆,精神分裂症或双相情感障碍的患者)死于COVID-19的风险有所增加。
更新日期:2021-04-14
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