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Plant RABs: Role in Development and in Abiotic and Biotic Stress Responses
Current Genomics ( IF 2.6 ) Pub Date : 2020-12-31 , DOI: 10.2174/1389202922666210114102743
Manas K Tripathy 1 , Renu Deswal 1 , Sudhir K Sopory 1
Affiliation  

Endosomal trafficking plays an integral role in various eukaryotic cellular activities and is vital for higher-order functions in multicellular organisms. RAB GTPases are important proteins that influence various aspects of membrane traffic, which consequently influence many cellular functions and responses. Compared to yeast and mammals, plants have evolved a unique set of plant-specific RABs that play a significant role in their development. RABs form the largest family of small guanosine triphosphate (GTP)-binding proteins, and are divided into eight sub-families named RAB1, RAB2, RAB5, RAB6, RAB7, RAB8, RAB11 and RAB18. Recent studies on different species suggest that RAB proteins play crucial roles in intracellular trafficking and cytokinesis, in autophagy, plant microbe interactions and in biotic and abiotic stress responses. This review recaptures and summarizes the roles of RABs in plant cell functions and in enhancing plant survival under stress conditions.



中文翻译:

植物RAB:在发育以及非生物和生物胁迫响应中的作用

内体运输在各种真核细胞活动中起着不可或缺的作用,对于多细胞生物中的高级功能至关重要。RAB GTPases是重要的蛋白质,会影响膜运输的各个方面,因此会影响许多细胞功能和反应。与酵母和哺乳动物相比,植物进化出了一套独特的植物特异性RAB,它们在它们的发育中起着重要作用。RAB形成了最大的小鸟苷三磷酸(GTP)结合蛋白家族,并分为八个亚家族,分别称为RAB1,RAB2,RAB5,RAB6,RAB7,RAB8,RAB11和RAB18。最近对不同物种的研究表明,RAB蛋白在细胞内运输和胞质分裂,自噬,植物微生物相互作用以及生物和非生物胁迫响应中起着至关重要的作用。

更新日期:2020-12-31
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