Purpose

To evaluate the ocular surface at the microstructural level of adults who habitually undertake indoor-suntanning utilising in vivo confocal microscopy.

Methods

Participants were prospectively recruited and enrolled into either а study group (n = 75) with a history UV indoor tanning, or a control group (n = 75) with no prior history of artificial tanning. The study group participated in voluntary tanning sessions performed with standard equipment and maintained their usual routine for eye protection. Slit lamp biomicroscopy and in vivo confocal microscopy were performed at baseline before undertaking a series of suntanning sessions (10 sessions of 10 min duration over a 15 day period), within three days after the last session, and four weeks after the last session. Control group participants were examined at baseline and 8 weeks later and did not participate in tanning sessions.

Results

All participants were female with a mean age of 25 ± 4 years and 24 ± 4 years in the study and control groups, respectively. No clinically significant changes were observed in either group over time using slit lamp biomicroscopy (all p ≥ 0.05), however, statistically significant differences were observed between the study and the control group for all corneal layers imaged using confocal microscopy (all p ≤ 0.03). Characteristic cystic conjunctival lesions with dark centres and bright borders were observed in 95% of the study group before and in 100% after the suntanning sessions.

Conclusion

Indoor suntanning resulted in statistically significant microstructural changes in the cornea and the bulbar conjunctiva that are undetectable with slit lamp biomicroscopy.

中文翻译：

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室内晒黑对眼表的损伤——来自体内共聚焦显微镜的见解

目的

使用体内共聚焦显微镜评估习惯性进行室内晒黑的成年人的显微结构水平的眼表。

方法

参与者被前瞻性地招募并纳入具有紫外线室内晒黑历史的研究组（n = 75）或没有人工晒黑历史的对照组（n = 75）。研究小组参加了使用标准设备进行的自愿晒黑课程，并保持他们通常的眼睛保护程序。裂隙灯生物显微镜和体内共聚焦显微镜在进行一系列日光浴（15 天期间 10 分钟，持续时间为 15 天）之前、最后一次疗程后三天内和最后一次疗程后 4 周内在基线处进行。对照组参与者在基线和 8 周后接受检查，并且没有参加美黑会议。

结果

研究组和对照组的所有参与者均为女性，平均年龄分别为 25±4 岁和 24±4 岁。随着时间的推移，使用裂隙灯生物显微镜在任一组中均未观察到临床显着变化（所有 p ≥ 0.05），但是，对于使用共聚焦显微镜成像的所有角膜层，在研究组和对照组之间观察到统计学上的显着差异（所有 p ≤ 0.03） . 研究组中 95% 的人在晒黑之前和 100% 的人在晒黑之前观察到特征性的囊性结膜病变，中心暗，边界亮。

结论

室内晒黑会导致角膜和球结膜出现统计学上显着的微观结构变化，这是裂隙灯生物显微镜无法检测到的。