The number of studies dealing with tertiary ozonation to remove trace organic contaminants (TrOCs) in effluents originating from wastewater treatment plants (WWTPs) is increasing due to the need for upgrading the WWTPs overall performance. To follow-up TrOCs removal in real-time during ozone-based treatment, online surrogate measurements are necessary, of which mainly spectroscopic surrogates (i.e. UV–VIS absorbance and fluorescence) are the emerging techniques in literature. This paper summarizes and reflects on the state-of-the-art as retrieved from more than 100 peer-reviewed studies published between January 2007 and December 2020 and dealing with (1) surrogate correlation models for the prediction of TrOCs removal in secondary effluent and (2) control strategies to adjust the ozone dose during (full-scale) operation. Next to the flow and load proportional ozone dosing strategies, controlling the ozone dose solely based on the characteristics of the effluent entering the ozonation unit, also a differential control strategy based on the change in characteristics due to ozonation of the WWTP effluent is highlighted. The latter seems the best option as flow and load proportional ozone dosing do not consider the amount and/or reactivity of the matrix constituents. The presence of organic and inorganic scavengers of ozone and radicals in the effluent matrix has a significant impact on the TrOCs removal efficiency. This effluent quality can differ in time and between WWTPs, hence the surrogate correlation models should be widely applicable. At the end of the review, recommendations are made for future research and implementation of an effective control strategy for (full-scale) applications.

由于需要升级污水处理厂的整体性能，有关三级臭氧化以去除废水处理厂（WWTP）产生的废水中痕量有机污染物（TrOCs）的研究数量正在增加。为了在基于臭氧的处理过程中实时跟踪去除TrOCs，必须进行在线替代物测量，其中主要是光谱替代物（即UV-VIS吸收和荧光）是文献中新兴的技术。本文总结并反映了从2007年1月至2020年12月之间发表的100余篇同行评审研究中检索到的最新技术，这些研究涉及（1）替代相关模型，用于预测次要废水中TrOCs的去除。 （2）控制策略，以在（满量程）运行期间调整臭氧剂量。除了流量和负荷成比例的臭氧定量给料策略外，仅根据进入臭氧化装置的废水的特性来控制臭氧剂量，还强调了基于污水处理厂废水因臭氧化而引起的特性变化的差异控制策略。后者似乎是最佳选择，因为按比例分配流量和负载的臭氧剂量不考虑基质成分的量和/或反应性。废水基质中臭氧和自由基的有机和无机清除剂的存在对TrOCs的去除效率有重大影响。污水质量在时间上和污水处理厂之间可能会有所不同，因此替代物相关模型应该广泛适用。在审查结束时，