Novel Schiff bases, Furan-2-carboxylic acid pyridin-4-ylmethyleneamide , and Thiophene-2-carboxylic acid 1H-indol-2-ylmethyleneamide and their mononuclear Ni(II) and Cu(II) complexes have been synthesized and characterized by elemental analysis, molar conductance, UV-visible, FT-IR, ¹H NMR and EPR spectroscopy. The complexes are non-electrolytes as evidenced from the molar conductance vaules. The ligands and their complexes have been tested for their antimicrobial activity against one gram positive bacteria, Bacillus subtilis, gram negative bacteria, Escherichia coli and fungi Candida albicans. It is found that metal complexes exhibited more activity than the free ligand.

中文翻译：

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新型席夫碱及其配合物的合成，表征和抗菌研究

合成了新型席夫碱，呋喃-2-羧酸吡啶-4-基亚甲基酰胺和噻吩-2-羧酸1H-吲哚-2-基亚甲基酰胺及其单核Ni（II）和Cu（II）配合物，并通过元素表征分析，摩尔电导，紫外可见，FT-IR，¹ H NMR和EPR光谱。如摩尔电导值所证明的，该络合物是非电解质。已经测试了配体及其复合物对一克阳性细菌，枯草芽孢杆菌，革兰氏阴性细菌，大肠杆菌和真菌白色念珠菌的抗菌活性。发现金属络合物显示出比游离配体更高的活性。