Magnesium (Mg) is widely used in different tissue engineering applications such as bone fracture fixations and cardiovascular stent applications. However, it exhibits high degradation properties in the physiological medium and hence loses its mechanical properties. Herein, AZ31 Mg alloy was spin-coated with polycaprolactone (PCL) polymer blended with Schiff base derived from amino acid as a corrosion inhibitor. Coated samples were characterized using field emission electron microscopy (FESEM) and Fourier-transform infrared spectroscopy (FTIR) analysis. Additionally, corrosion behavior was evaluated using electrochemical potentiodynamic polarization and electrochemical impedance spectroscopy (EIS) techniques. Moreover, the bioactivity of the studied samples was confirmed in vitro with MC3T3-E1 osteoblasts cells. Results show that coated samples with corrosion inhibition efficiency of blended PCL and L-isoleucine Schiff (PCL-SI) reached 66% compared to that of pure PCL 39%. This suggests that the introduced materials were superior to control biodegradability and biocompatibility of the bare alloy in bone tissue engineering application.

镁（Mg）广泛用于不同的组织工程应用，例如骨折固定和心血管支架应用。但是，它在生理介质中表现出高降解性能，因此失去了其机械性能。在此，在AZ31 Mg合金上旋涂聚己内酯（PCL）聚合物，该聚合物与作为腐蚀抑制剂的源自氨基酸的席夫碱混合。使用场发射电子显微镜（FESEM）和傅立叶变换红外光谱（FTIR）分析对涂层样品进行表征。此外，使用电化学势动力极化和电化学阻抗谱（EIS）技术评估了腐蚀行为。此外，在体外用MC3T3-E1成骨细胞证实了所研究样品的生物活性。L-异亮氨酸Schiff（PCL-SI）达到66％，而纯PCL为39％。这表明引入的材料在骨组织工程应用中优于控制裸合金的生物降解性和生物相容性。