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Model eye tool for retinal optical coherence tomography instrument calibration
Journal of Innovative Optical Health Sciences ( IF 2.5 ) Pub Date : 2021-04-07 , DOI: 10.1142/s1793545821500103
Hongting Wang 1 , Wenli Liu 1 , Zhixiong Hu 1 , Xiuyu Li 1 , Fei Li 1 , Liangcheng Duan 1
Affiliation  

Optical coherence tomography (OCT) has been extensively used as noninvasive tool for biological tissues owing to its three-dimensional imaging ability and high axial resolution. OCT quality assurance is vital in these occasions to keep the reliability and accuracy in medical diagnosis. It is necessary to develop a calibration tool for OCT product manufacture, calibration, and quality control. A practical tool is demanded in the OCT quality control and calibration of OCT. So far, there is no such a practical tool that can test all the key parameters of OCT. We design and fabricate a model eye tool, which has this function. The model eye comprises a doublet lens, a single filament, a piece of glass plate and the microsphere-embedded phantom. The doublets lens is bonded by two pieces of planoconvex lenses in the plane position. The first lens focuses parallel light onto the rear surface of the second lens. The rear surface marked with concentric circles serves as retina to measure the angular field of view (FOV). The small flat surface on the peak of the second lens is used to test signal to noise ratio (SNR). The single filament with 125μm diameter is used to check the co-alignment of preview and OCT scan. The empty chamber between the small plane of the second lens and the first surface of glass plate is used to measure the depth scaling of the OCT. The microspheres of 1μm diameter distributed uniformly in the phantom, which can test the lateral and the axial resolution of OCT equipment. Experimental results are presented to show the validity of the proposed tool. It is shown that the tool is able to be used in the calibration and quality control of retinal OCT.

中文翻译:

用于视网膜光学相干断层扫描仪校准的模型眼工具

光学相干断层扫描(OCT)由于其三维成像能力和高轴向分辨率,已被广泛用作生物组织的无创工具。在这些情况下,OCT 质量保证对于保持医疗诊断的可靠性和准确性至关重要。有必要开发用于OCT产品制造、校准和质量控制的校准工具。OCT的质量控制和校准需要一个实用的工具。到目前为止,还没有一个实用的工具可以测试 OCT 的所有关键参数。我们设计并制作了具有此功能的模型眼睛工具。模型眼睛包括双透镜、单灯丝、一块玻璃板和嵌入微球的模型。双合透镜由平面位置的两片平凸透镜粘合而成。第一透镜将平行光聚焦到第二透镜的后表面。用同心圆标记的后表面用作视网膜以测量视场角 (FOV)。第二个透镜顶部的小平面用于测试信噪比(SNR)。125单丝μm 直径用于检查预览和 OCT 扫描的对齐情况。第二透镜的小平面和玻璃板的第一表面之间的空腔用于测量OCT的深度缩放。微球 1μm直径均匀分布在体模中,可以测试OCT设备的横向和轴向分辨率。实验结果展示了所提出的工具的有效性。结果表明,该工具可用于视网膜 OCT 的校准和质量控制。
更新日期:2021-04-07
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