As molecular profiling of renal cell carcinoma (RCC) continues to elucidate novel targets for nonclear cell histologies, understanding the landscape of these targets is of utmost importance. In this review, we highlight the genomic landscape of nonclear cell RCC and its implications for current and future systemic therapies.

中文翻译：

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一个具有挑战性的前沿——非透明细胞肾细胞癌的基因组学和治疗学。

随着肾细胞癌 (RCC) 的分子谱分析不断阐明非透明细胞组织学的新靶点，了解这些靶点的概况至关重要。在这篇综述中，我们重点介绍了非透明细胞 RCC 的基因组概况及其对当前和未来全身治疗的影响。