Susceptibility weighted imaging (SWI) and resting state functional magnetic resonance imaging have been highlighted as two novel neuroimaging modalities that have been underutilized when attempting to predict whether a child with concussion will recover normally or have a delayed recovery course. This study aimed to investigate whether there was a difference between children who recover normally from a concussion and children with delayed recovery in terms of SWI lesion burden and resting state network makeup. Forty-one children who presented to the emergency department of a tertiary level pediatric hospital with concussion participated in this study as a part of a larger prospective, longitudinal observational cohort study into concussion assessment and recovery. Children underwent neuroimaging 2 weeks post-injury and were classified as either normally recovering (n = 27), or delayed recovering (n = 14) based on their post-concussion symptoms at 2 weeks post-injury. No participants showed lesions detected using SWI; therefore, no group differences could be assessed. No between-group resting state network differences were uncovered using dual regression analysis. These findings, alongside previously published work, suggest that potential causes of delayed recovery from concussion may not be found using current neuroimaging paradigms.

中文翻译：

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没有证据表明脑震荡后两周典型恢复延迟儿童之间的磁敏感加权成像病变负担或功能网络连接存在差异

磁敏加权成像（SWI）和静息态功能磁共振成像被认为是两种新颖的神经影像学模式，在试图预测脑震荡儿童是否会正常恢复或恢复过程延迟时，这些模式尚未得到充分利用。本研究旨在调查从脑震荡中正常恢复的儿童和延迟恢复的儿童在 SWI 损伤负担和静息状态网络构成方面是否存在差异。41 名因脑震荡而到三级儿科医院急诊科就诊的儿童参加了这项研究，作为脑震荡评估和恢复的更大前瞻性、纵向观察队列研究的一部分。n = 27)，或 根据受伤后 2 周的脑震荡后症状 延迟恢复 ( n = 14)。没有参与者表现出使用 SWI 检测到的病变；因此，无法评估群体差异。使用双重回归分析未发现组间静息状态网络差异。这些发现以及之前发表的研究表明，使用当前的神经影像范式可能无法找到脑震荡延迟恢复的潜在原因。