In this review, we present literature describing the use of polypyrroles as an alternative to traditional surface modification methods for detecting oligonucleotides. The methodology used to immobilize and differentiate analytes on conducting surfaces as well as the resulting changes in the electrochemical properties of the polypyrrole-coated-electrodes will be discussed. Through the electropolymerization process, an applied potential permits radical cation propagation to produce doped electroactive polymers. The electrochemical properties exhibited by polypyrroles have been exploited for the detection and quantification of analytes in multiple disciplines. Taking advantage of the stability and excellent adhesive properties on electrode surfaces, functionalization of polypyrroles allows binding of oligonucleotide probes and thus detection of DNA targets.

在这篇综述中，我们介绍了描述使用聚吡咯作为检测寡核苷酸的传统表面修饰方法的替代方法的文献。将讨论用于固定和区分导电表面上的分析物的方法，以及由此产生的聚吡咯涂层电极的电化学性能变化。通过电聚合过程，施加的电势可使自由基阳离子传播，从而产生掺杂的电活性聚合物。聚吡咯表现出的电化学性质已被用于多种学科中检测和定量分析物。利用电极表面的稳定性和出色的粘合性能，