Abstract

The innate immune system plays a vital role to resist the environmental stresses and infectious pathogens in marine mammal pups. To get a baseline level of innate immune capacity in spotted seals, the concentrations of several antioxidant and immune-related factors in the serum of wild and captive spotted seal (Phoca largha) pups from the Liaodong Bay colony were measured and compared. Cu/Zn superoxide dismutase and peroxidase were mainly responsible for the antioxidant system of spotted seal pups, and wild pups possessed stronger antioxidant capacity than captive ones. Against infectious pathogens, wild spotted seal pups also had an advantage over the captive counterparts. Specifically, the activities of acid phosphatase, phenoloxidase, and lysozyme in the serum of wild spotted seal pups were significantly higher than those in captive animals. The present study provides the normal activities of several serum immune enzymes for wild and captive spotted seal pups from the Liaodong Bay colony, which is benefit to the conservation of this species.

中文翻译：

---

辽东湾殖民地野生和圈养海豹幼崽血清抗氧化酶活性和免疫因子的差异。

摘要

天生的免疫系统在抵抗环境压力和海洋哺乳动物幼崽中的传染性病原体方面起着至关重要的作用。为了获得斑点海豹的先天免疫能力的基线水平，应了解野生和圈养斑点海豹（Phoca largha）血清中几种抗氧化剂和免疫相关因子的浓度对来自辽东湾殖民地的幼崽进行了测量和比较。铜/锌超氧化物歧化酶和过氧化物酶主要负责斑海豹幼崽的抗氧化系统，而野生幼崽的抗氧化能力强于圈养幼崽。与传染性病原体相比，野生斑点海豹幼崽也比圈养海豹幼崽具有优势。具体而言，野生斑点海豹幼崽血清中的酸性磷酸酶，酚氧化酶和溶菌酶的活性显着高于圈养动物。本研究为辽东湾殖民地野生和圈养斑海豹幼崽提供了几种血清免疫酶的正常活性，这有利于该物种的保存。