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Polysaccharides from Marine Algae in Modern Technologies of Regenerative Medicine
Russian Journal of Marine Biology ( IF 0.6 ) Pub Date : 2021-04-05 , DOI: 10.1134/s1063074021010065
T. A. Kuznetsova , B. G. Andryukov , N. N. Besednova , Yu. S. Khotimchenko

Abstract

The present review considers the physicochemical and biological properties of polysaccharides (PSs) obtained from marine algae (alginates and fucoidans from brown algae; carrageenans from red algae; and ulvans from green algae). These PSs are used in the latest technologies of regenerative medicine (tissue engineering, modulation of drug delivery system, and design of wound dressing materials). Special attention is paid to the ability of PS to form hydrogels, as hydrogel dressings meet the basic requirements for a perfect wound dressing. This review discusses the current trends in the development of a new generation of PS-based materials for creation of drug delivery systems and various tissue-engineering scaffolds; this approach allows one to create human-specific tissues and to develop target-oriented and personalized regenerative medicine products.



中文翻译:

现代再生医学技术中海藻中的多糖

摘要

本综述考虑了从海藻(褐藻中的藻酸盐和岩藻依聚糖;红藻中的角叉菜胶;绿藻中的ulvans)获得的多糖(PSs)的理化和生物学特性。这些PS用于再生医学的最新技术(组织工程,药物输送系统的调节以及伤口敷料的设计)。特别注意PS形成水凝胶的能力,因为水凝胶敷料满足完美伤口敷料的基本要求。这篇综述讨论了用于生产药物递送系统和各种组织工程支架的新一代基于PS的材料的发展趋势;

更新日期:2021-04-06
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