Vesicles, generally defined as self-assembled structures formed by single or multiple concentric bilayers that surround an aqueous core, have been widely used for biomedical applications. They can either occur naturally (e.g. exosomes) or be produced artificially and range from the micrometric scale to the nanoscale. One the most well-known vesicle is the liposome, largely employed as a drug delivery nanocarrier. Liposomes have been modified along the years to improve physicochemical and biological features, resulting in long-circulating, ligand-targeted and stimuli-responsive liposomes, among others. In this process, new nomenclatures were reported in an extensive literature. In many instances, the new names suggest the emergence of a new nanocarrier, which have caused confusion as to whether the vesicles are indeed new entities or could simply be considered modified liposomes. Herein, we discussed the extensive nomenclature of vesicles based on the suffix “some” that are employed for drug delivery and composed of various types and proportions of lipids and others amphiphilic compounds. New names have most often been selected based on changes of vesicle lipid composition, but the payload, structural complexity (e.g. multicompartment) and new/improved proprieties (e.g. elasticity) have also inspired new vesicle names. Based on this discussion, we suggested a rational classification for vesicles.

囊泡，通常定义为由围绕水核的单个或多个同心双层形成的自组装结构，已广泛用于生物医学应用。它们既可以天然存在（例如外泌体），也可以人工产生，范围从微米级到纳米级。最著名的囊泡之一是脂质体，主要用作药物递送纳米载体。多年来，脂质体已经被修改以改善物理化学和生物学特性，从而产生长循环、配体靶向和刺激响应的脂质体等。在此过程中，大量文献报道了新的命名法。在许多情况下，新名称暗示了一种新的纳米载体的出现，这引起了人们对囊泡是否确实是新实体或是否可以简单地被认为是修饰的脂质体的混淆。在这里，我们讨论了基于后缀“some”的囊泡的广泛命名法，这些囊泡用于药物递送，由各种类型和比例的脂质和其他两亲性化合物组成。新名称通常是根据囊泡脂质组成的变化来选择的，但有效载荷、结构复杂性（例如多室）和新的/改进的特性（例如弹性）也激发了新的囊泡名称。基于此讨论，我们建议对囊泡进行合理分类。我们讨论了基于后缀“some”的囊泡的广泛命名法，这些囊泡用于药物输送，由各种类型和比例的脂质和其他两亲化合物组成。新名称通常是根据囊泡脂质组成的变化来选择的，但有效载荷、结构复杂性（例如多室）和新的/改进的特性（例如弹性）也激发了新的囊泡名称。基于此讨论，我们建议对囊泡进行合理分类。我们讨论了基于后缀“some”的囊泡的广泛命名法，这些囊泡用于药物输送，由各种类型和比例的脂质和其他两亲化合物组成。新名称通常是根据囊泡脂质组成的变化来选择的，但有效载荷、结构复杂性（例如多室）和新的/改进的特性（例如弹性）也激发了新的囊泡名称。基于此讨论，我们建议对囊泡进行合理分类。