This review discusses the accumulated evidence that pro-opiomelanocortin (POMC) gene products as well as other pituitary neuropeptides derived from related genes (Proenkephalin, PENK; Prodynorphin, PDYN, and Pronociceptin, PNOC) can exert direct effects on B lymphocytes to modulate their functions. We also review the available data on receptor systems that might be involved in the transmission of such hormonal signals to B cells.

中文翻译：

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垂体神经肽和 B 淋巴细胞功能

本综述讨论了积累的证据，即阿片黑素皮质素原 (POMC) 基因产物以及其他源自相关基因（脑啡肽原、PENK；强啡肽原、PDYN 和 Pronociceptin、PNOC）的垂体神经肽可以直接作用于 B 淋巴细胞以调节其功能. 我们还审查了有关受体系统的可用数据，这些数据可能参与将此类激素信号传输到 B 细胞。