Background

The National Clinical Database (NCD) nationwide registry program of gastric cancer started in 2018. The purpose of this study was to report the treatment results of the NCD registry in the form of treatment results of the real world in Japan.

Methods

Patients’ characteristics, tumor features, treatments, and outcomes were collected using a web-based data entry system. We analyzed the initial NCD database for data on surgically treated gastric cancer patients in 2011.

Results

A total of 30,257 patients with malignant gastric tumors were enrolled by the NCD registry program from 501 hospitals in all 47 prefectures. Of these, the status of data entry was not approved in 8.8% of the registered data, and follow-up information was missing in 1.2% of the approved cases. Excluding 1777 cases, which were not resected for primary gastric cancer, 25,306 resected cases included 44.4% of stomach surgeries recorded in the NCD. The 5 year survival rate of the resected cases was 71.3% and the operative mortality rate was 0.41%. The stage-specific 5 year survival rates were as follows: 89.6% for stage IA, 83.8% for stage IB, 77.3% for stage IIA, 69.1% for stage IIB, 58.7% for stage IIIA, 44.1% for stage IIIB, 30.1% for stage IIIC, and 13.4% for stage IV.

Conclusions

The NCD gastric cancer registry program demonstrated validity for database construction. The gastric cancer registry is expected to become a nationwide registry with the dissemination of data entry system and method in the NCD.

中文翻译：

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日本手术治疗胃癌：国家临床数据库胃癌登记处2011年年度报告

背景

国家临床数据库（NCD）全国胃癌登记计划于2018年启动。本研究的目的是在日本以真实世界的治疗结果的形式报告NCD登记的治疗结果。

方法

使用基于网络的数据输入系统收集患者的特征、肿瘤特征、治疗和结果。我们分析了 2011 年接受手术治疗的胃癌患者数据的初始 NCD 数据库。

结果

NCD 登记项目共招募了 30,257 名来自所有 47 个地县的 501 家医院的恶性胃肿瘤患者。其中，8.8%的注册数据未获批数据录入状态，1.2%的获批数据缺失后续信息。排除原发胃癌未切除的 1777 例，25306 例切除的病例占 NCD 记录的胃手术的 44.4%。切除病例5年生存率为71.3%，手术死亡率为0.41%。分期特异性 5 年生存率如下：IA 期 89.6%，IB 期 83.8%，IIA 期 77.3%，IIB 期 69.1%，IIIA 期 58.7%，IIIB 期 44.1%，30.1% IIIC 期，IV 期 13.4%。

结论

NCD 胃癌登记计划证明了数据库构建的有效性。随着NCD数据录入系统和方法的传播，胃癌登记处有望成为全国性的登记处。