High throughput (HT) screening techniques for pressure-driven membrane processes allow simultaneous screening of multiple membrane samples under similar conditions, and are thus labour-, time- and consumables efficient. HT-modules have so far all been set-up in dead-end configuration. A new filtration set-up for cross-flow filtration has now been designed, allowing to simultaneously perform 16 pressure-driven separations with a membrane surface of 15 cm² each. The potential of the developed equipment and of the HT-screening concept in general was validated by demonstrating the reliability and reproducibility of the measurement of membrane performances, and by comparing flow simulations and experimental data. These data were obtained with 2 types of commercially available membrane: a nanofiltration membrane (NF 270, DowDuPont, USA) and a reverse osmosis membrane 73AC-UTC (Toray Industries Inc., Japan). Additionally, the flow-regime inside the cross-flow channel was studied by varying the hydrodynamic parameters and by applying feed spacers. The reproducibility of the data proved that this HT-approach can be a useful tool to rapidly screen a large array of operational parameters in membrane processes.

用于压力驱动膜工艺的高通量（HT）筛查技术允许在相似条件下同时筛查多个膜样品，因此高效，省力，省时且易耗。到目前为止，HT模块都已全部设置为死端配置。现在已经设计出一种新的错流过滤装置，可以同时进行16个压力驱动的分离，每个分离的膜面积为15cm²。通过证明膜性能测量的可靠性和可重复性，以及通过比较流动模拟和实验数据，可以验证所开发设备和HT筛选概念的潜力。这些数据是通过两种类型的市售膜获得的：纳滤膜（NF 270，DowDuPont，美国）和反渗透膜73AC-UTC（日本Toray Industries Inc.）。另外，通过改变流体动力学参数并使用进料隔垫来研究错流通道内部的流态。数据的可重复性证明，这种HT方法可以作为一种有用的工具，用于快速筛选膜工艺中的大量操作参数。