Two types of long-chained pyridinium N-chloramines were designed and synthesised by covalent linking a N-chloramine unit and a long intact alkyl chain via varied alkylation of 3-hydroxypyridine. Preliminary antibacterial tests showed that both synthetic pyridinium N-chloramines exerted distinctively elevated biocidal efficacy in contrast to previously reported pyridinium N-chloramines that lack a long chain. Such enhanced bactericidal behaviour was probably caused by ‘synergistic’ biocidal action between the N-chloramine moiety and the long-chained pyridinium moiety.

中文翻译：

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长链吡啶鎓N-氯胺类化合物：抗菌应用的合成和显着的杀菌功效。

通过3-羟基吡啶的不同烷基化作用，共价连接N-氯胺单元和完整的长烷基链，设计并合成了两种类型的长链吡啶鎓N-氯胺。初步的抗菌试验表明，这两种合成的吡啶鎓Ñ -chloramines对比先前报道的吡啶施加区别地升高杀生物效力Ñ缺乏长链-chloramines。这种增强的杀菌行为可能是由于N-氯胺部分和长链吡啶鎓部分之间的“协同”杀生物作用引起的。