A breast cancer hyperthermia system has been developed for the targeted of increasing hyperthermia therapy efficiency after lumpectomy surgery with the assistance of fat grafting technique. Enhancing the efficiency of hyperthermia treatment will decrease the required radiation doses after surgery. A fat grafting technique is applied around the tumor region that is located into glandular tissue for the purpose of enhancing wave penetration through glandular tissue. The proposed hyperthermia system employs a single horn antenna operating at 2.45 GHz. Here, a modified hyperthermia system was tested on a hemisphere phantom of two different densities with various tumor sizes at depth 2.8 cm from skin layer. Transmission and reflection coefficients of applied electromagnetic waves at the air‐phantom interface were calculated analytically. Based on these computations, an external dielectric matched layer was added on the skin layer of breast to decrease reflection that would occur at the skin layer because of the difference in permittivity values. The experiments were conducted on a 3‐D phantom that has the realistic dielectric properties using the available laboratory capability. Measured and simulated results confirmed the system ability to increase the diseased region temperature using fat grafting technique with a dielectric matched layer without increasing the system input power.

中文翻译：

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利用角天线脂肪移植提高微波乳腺癌的高温治疗效率

已经开发了一种乳腺癌热疗系统，其目标是在脂肪移植技术的辅助下，在乳房切除术后提高热疗的治疗效率。提高高温治疗的效率将减少手术后所需的放射剂量。为了增强波通过腺组织的穿透力，在位于腺组织内的肿瘤区域周围应用了脂肪移植技术。所提出的热疗系统采用在2.45 GHz下运行的单号角天线。在这里，在距皮肤层2.8 cm的深度，具有不同肿瘤大小的两种不同密度的半球体模上测试了改良的高温系统。通过分析计算了在空气-幻象界面处施加的电磁波的透射系数和反射系数。基于这些计算，外部介电匹配层被添加到乳房的皮肤层上，以减少由于介电常数值的不同而在皮肤层上发生的反射。使用可用的实验室功能，在具有逼真的介电特性的3D幻像上进行了实验。测量和模拟结果证实了系统具有使用具有介电匹配层的脂肪接枝技术来增加患病区域温度的能力，而不会增加系统输入功率。使用可用的实验室功能，在具有逼真的介电特性的3D幻像上进行了实验。测量和模拟结果证实了系统具有使用具有介电匹配层的脂肪接枝技术提高患病区域温度的能力，而不会增加系统输入功率。使用可用的实验室功能，在具有逼真的介电特性的3D幻像上进行了实验。测量和模拟结果证实了系统具有使用具有介电匹配层的脂肪接枝技术提高患病区域温度的能力，而不会增加系统输入功率。