Nano-Structures & Nano-Objects Pub Date : 2021-04-01 , DOI: 10.1016/j.nanoso.2021.100724 Moorthy Maruthapandi , Poushali Das , Arumugam Saravanan , Michal Natan , Ehud Banin , Sriram Kannan , Shulamit Michaeli , John H.T. Luong , Aharon Gedanken
Plant leaves have more attracted in the preparation of carbon dots (CDs) owing to natural phytochemicals. Herein, we performed a one-pot hydrothermal process for the synthesis of Nitrogen doped CDs (N@CDs) from glossy heart-shaped Piper betel leaves (P. betel). The prepared N@CDs were effectively applied for the eradication of E. coli, S. aureus, and methicillin-resistant S. aureus (MRSA). The N@CDs were also used as a sensor for lanthanides detection with notable selectivity for Eu3+. The results revealed that the water-soluble N@CDs displayed narrow size particle distribution with a mean diameter of 2.6 nm. The bright fluorescence was estimated to be at : 350 with : 430 nm. The functional groups on N@CDs were confirmed by FTIR and XPS. The antimicrobial effect of N@CDs was concentration-dependent and effectively against E. coli and S. aureus at 1000 g/mL. The antibacterial results reveal that the N@CDs exhibit the selective and superior killing effect against antibiotic-resistant bacteria (MRSA). The biocompatibility of CDs explored using THP- 1 monocytes cells. The N@CDs were also applicable for sensitive and selective detection of Eu3+ with LOD of 68 M over other lanthanides in an aqueous solution by fluorescence quenching.
中文翻译:
生物相容性的氮掺杂碳点,用于消除耐甲氧西林的金黄色葡萄球菌(MRSA)和sensitive(III)的灵敏分析
由于天然植物化学成分,植物叶片在碳点(CD)的制备中更具吸引力。在这里,我们执行了一锅水热法,从有光泽的心形Piper槟榔叶(P. betel)合成了氮掺杂的CD(N @ CDs )。制备的N @ CDs有效地用于根除大肠杆菌,金黄色葡萄球菌和耐甲氧西林的金黄色葡萄球菌(MRSA)。N @ CD还用作镧系元素检测的传感器,对Eu 3+具有显着的选择性。结果表明,水溶性N @ CDs的粒径分布较窄,平均直径为2.6 nm。明亮的荧光估计为:350与 :430nm。N @ CDs上的官能团已通过FTIR和XPS确认。N @ CDs的抗菌作用是浓度依赖性的,并在1000 ℃时有效抵抗大肠杆菌和金黄色葡萄球菌。克/毫升。抗菌结果表明,N @ CD对抗生素抗性细菌(MRSA)表现出选择性和优异的杀灭作用。使用THP-1单核细胞探索CD的生物相容性。N @ CD也适用于灵敏度和选择性检测Eu 3 +,LOD为68通过荧光猝灭使水溶液中的M超过其他镧系元素。