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Mechanism underlying sevoflurane-induced protection in cerebral ischemia–reperfusion injury
Open Chemistry ( IF 2.3 ) Pub Date : 2021-01-01 , DOI: 10.1515/chem-2021-0045
Bing Chen 1 , Minqiu Lin 1 , Simiao Chen 1 , Weiyan Chen 2 , Jingmei Song 2 , Yuyan Zhang 1
Affiliation  

Cerebral ischemia is an extremely complex disease that can be caused by a variety of factors. Cerebral ischemia can cause great harm to human body. Sevoflurane is a volatile anesthetic that is frequently used in clinic, and has a lot of advantages, such as quick induction of general anesthesia, quick anesthesia recovery, no respiratory tract irritation, muscle relaxation, and small cycle effect. The mechanism of sevoflurane preconditioning or post-treatment induction is poorly understood. The purpose of this study was to illustrate the mechanism underlying sevoflurane-induced protection in cerebral ischemia–reperfusion injury and also provide theoretical guidance for future research.

中文翻译:

七氟醚诱导的脑缺血再灌注损伤保护机制

脑缺血是一种非常复杂的疾病,可以由多种因素引起。脑缺血可对人体造成极大伤害。七氟醚是一种挥发性麻醉药,在临床上经常使用,并具有许多优点,例如快速诱导全身麻醉,快速麻醉恢复,无呼吸道刺激,肌肉松弛和小周期效应。七氟醚预处理或后处理诱导的机制了解甚少。本研究的目的是阐明七氟醚诱导的脑缺血再灌注损伤保护机制,并为将来的研究提供理论指导。
更新日期:2021-01-01
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