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Comparison of Endoscopic Techniques in the Management of Type I Gastric Neuroendocrine Neoplasia: A Systematic Review
Gastroenterology Research and Practice ( IF 2 ) Pub Date : 2021-03-31 , DOI: 10.1155/2021/6679397
Francesco Panzuto 1 , Ludovica Magi 1, 2 , Gianluca Esposito 1, 3 , Maria Rinzivillo 1 , Bruno Annibale 1, 3
Affiliation  

Background. Endoscopic resection is considered the treatment of choice for type I gastric neuroendocrine neoplasia (gNEN) given its indolent behaviour; however, the favoured endoscopic technique to remove these tumours is not well established. Aims. This systematic review is aimed at investigating the best endoscopic management for type I gNEN. Methods. PubMed Central/Medline and Scopus were systematically searched for records up to August 31, 2020. Results. After screening the 675 retrieved records, 6 studies were selected for the final analysis. The main endoscopic resection techniques described were endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD). Overall, 112 gNENs were removed by EMR and 77 by ESD. Both techniques showed similar results for complete and en bloc resection (97.4% and 98.7%; 92.3% and 96.3% with ESD and EMR, respectively). ESD was associated with a higher rate of complications than EMR (11.7% vs. 5.4%), but this difference was not statistically significant (). The rates of recurrence during follow-up were 18.2% and 11.5% for EMR and ESD, respectively. Conclusions. To date, there are no sufficient data showing superiority of a given endoscopic technique over others. Both ESD and EMR seem to be effective in the management of type I gNEN, with a relatively low rate of recurrence.

中文翻译:

内窥镜技术在 I 型胃神经内分泌瘤治疗中的比较:系统评价

背景。鉴于其惰性行为,内镜切除被认为是 I 型胃神经内分泌瘤 (gNEN) 的首选治疗方法;然而,用于切除这些肿瘤的首选内窥镜技术尚未得到充分确立。目标。本系统评价旨在调查 I 型 gNEN 的最佳内镜管理。方法。PubMed Central/Medline 和 Scopus 系统地搜索了截至 2020 年 8 月 31 日的记录。结果. 筛选675条检索记录后,选择6项研究进行最终分析。描述的主要内窥镜切除技术是内窥镜黏膜切除术 (EMR) 和内窥镜黏膜下剥离术 (ESD)。总体而言,EMR 去除了 112 个 gNEN,ESD 去除了 77 个。两种技术对完全切除和整块切除的结果相似(分别为 97.4% 和 98.7%;ESD 和 EMR 分别为 92.3% 和 96.3%)。与 EMR 相比,ESD 与更高的并发症发生率相关(11.7% 对 5.4%),但这种差异无统计学意义()。随访期间 EMR 和 ESD 的复发率分别为 18.2% 和 11.5%。结论。迄今为止,没有足够的数据显示给定内窥镜技术优于其他技术。ESD 和 EMR 似乎都对 I 型 gNEN 的管理有效,且复发率相对较低。
更新日期:2021-03-31
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