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Perfluorocarbon nanomaterials for photodynamic therapy
Current Opinion in Colloid & Interface Science ( IF 8.9 ) Pub Date : 2021-03-31 , DOI: 10.1016/j.cocis.2021.101454
Rachael A Day 1 , Ellen M Sletten 1
Affiliation  

Photodynamic therapy (PDT) is a treatment modality in which a photosensitizer is irradiated with light, producing reactive oxygen species, often via energy transfer with oxygen. As it is common for tumors to be hypoxic, methods to deliver photosensitizer and oxygen are desirable. One such approach is the use of perfluorocarbons, molecules in which all C–H bonds are replaced with C–F bonds, to co-deliver oxygen because of the high solubility of gases in perfluorocarbons. This review highlights the benefits and limitations of several fluorinated nanomaterial architectures for use in PDT.



中文翻译:

用于光动力治疗的全氟化碳纳米材料

光动力疗法 (PDT) 是一种治疗方式,其中光敏剂被光照射,产生活性氧物质,通常通过与氧气的能量转移。由于肿瘤通常缺氧,因此需要提供光敏剂和氧气的方法。其中一种方法是使用全氟化碳(其中所有 C-H 键都被 C-F 键取代的分子)来共同传递氧气,因为气体在全氟化碳中具有高溶解度。本综述强调了几种用于 PDT 的氟化纳米材料结构的优点和局限性。

更新日期:2021-05-19
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