Although Japanese radish (Raphanus sativus L.) is a common Japanese ingredient, there are few reports of IgE-mediated immediate food allergy caused by Japanese radish. A 48-year-old woman developed urticarial lesions on her hands after grating Japanese radish and also developed lip edema and oral itching when she ate a salad composed of raw Japanese radishes. Skin prick testing was positive to extract of grated Japanese radish. Moreover, immunoblotting analysis showed IgE reactivity in the patient’s serum to a single band at the 18 kDa in grated Japanese radish, suggesting that the heat-labile 18 kDa protein of raw Japanese radish may be a radish-specific antigen. To the best of our knowledge, this is the first case report of a patient with hand urticaria, lip angioedema, and oropharyngeal pruritus to raw Japanese radish through IgE-mediated immediate allergic reaction.

中文翻译：

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通过IgE介导的立即变态反应由日本萝卜引起的手荨麻疹，唇血管水肿和口咽瘙痒症

尽管日本萝卜（Raphanus sativus L.）是一种常见的日本成分，但鲜有关于IgE介导的由日本萝卜引起的食物过敏的报道。一名48岁的女性在磨碎日本萝卜后，手上出现荨麻疹皮损，并且在吃了由日本萝卜制成的色拉时，也出现了唇部浮肿和口腔瘙痒。皮肤点刺试验对切碎的日本萝卜提取物呈阳性。此外，免疫印迹分析表明，患者的血清中的IgE反应性对日本萝卜丝中18 kDa处的单个条带具有响应性，这表明日本萝卜生的对热不稳定的18 kDa蛋白可能是萝卜特异的抗原。据我们所知，这是手部荨麻疹，嘴唇血管性水肿，