Objective: We evaluated the efficacy of electroacupuncture combined with tropisetron in treating carboprost tromethamine-induced nausea and vomiting during cesarean section under lumbar anesthesia. Methods: A total of 264 patients aged 22–40 years were enrolled, who received carboprost tromethamine and suffered nausea and vomiting during cesarean section under lumbar anesthesia. The patients were divided randomly into the control group, electroacupuncture group, tropisetron group, and electroacupuncture + tropisetron group. Results: Compared to the control group, the nausea and vomiting scores decreased at T₃ in both the electroacupuncture and electroacupuncture + tropisetron groups, and decreased at T₄ in the electroacupuncture group, tropisetron group, and electroacupuncture + tropisetron group; the motilin, gastrin, and 5-hydroxytryptamine (5-HT) levels decreased at T₅ in the other 3 groups. Compared to the electroacupuncture + tropisetron group, the nausea and vomiting scores increased at T₃ in the control and tropisetron groups, and increased at T₄ in the other 3 groups; the motilin, gastrin, and 5-HT levels increased at T₅. Conclusions: Our study suggested that electroacupuncture combined with tropisetron could effectively relieve carboprost tromethamine-induced nausea and vomiting during cesarean section under lumbar anesthesia. The effect was better than its single application, and the reduced 5-HT, motilin, and gastrin levels might be involved in the underlying mechanism.
Complement Med Res

中文翻译：

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电针联合托烷司琼治疗腰麻剖宫产期间卡前列素氨丁三醇所致恶心呕吐的疗效观察

目的：评价电针联合托烷司琼治疗腰麻下剖宫产时卡前列素氨丁三醇所致恶心呕吐的疗效。方法：共纳入264例22～40岁接受卡前列素氨丁三醇并在腰麻下剖宫产时出现恶心、呕吐的患者。将患者随机分为对照组、电针组、托烷司琼组、电针+托烷司琼组。结果：与对照组相比，电针组和电针+托烷司琼组恶心呕吐评分均在T ₃时下降，并在T _{4 时}下降。电针组、托烷司琼组、电针+托烷司琼组；其他 3 组的胃动素、胃泌素和 5-羟色胺 (5-HT) 水平在 T ₅时下降。与电针+托烷司琼组比较，对照组和托烷司琼组恶心呕吐评分在T ₃时升高，其他3组在T ₄时升高；胃动素、胃泌素和 5-HT 水平在 T _{5 时}增加。结论：我们的研究表明，电针联合托烷司琼可有效缓解卡前列素氨丁三醇引起的腰麻剖宫产恶心呕吐。其效果优于单次应用，5-HT、胃动素和胃泌素水平降低可能与其作用机制有关。
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