Pollution of the marine environment has been increasing as a result of anthropogenic activities. The preservation of marine ecosystems as well as the safety of harvested seafood are nowadays a global concern. In the present study, levels of pharmaceuticals and personal care products were assessed in different environmental compartments in the near-shore marine environment of False Bay, Cape Town, South Africa. The study revealed the presence of these persistent chemical compounds in different environmental samples from this location. Diclofenac was the most dominant compound detected, with higher concentration than the other pharmaceutical compounds, as well as being present in almost all the samples from the different sites (seawater, 3.70–4.18 ng/L; sediment, 92.08–171.89 ng/g dry wt; marine invertebrates, 67.67–780.26 ng/g dry wt; seaweed, 101.50–309.11 ng/g dry wt). The accumulation of pharmaceuticals and personal care products in the different species of organisms reflects the increasing anthropogenic pressure taking place at the sampling sites along the bay, as a result of population growth, resident lifestyle as well as poorly treated sewage effluent discharge from several associated wastewater-treatment plants. The concentration of these contaminants is in the order marine biota > sediments > seawater. The contaminants pose a low acute and chronic risk to the selected trophic levels. A public awareness campaign is needed to reduce the pollution at the source, as well as wastewater discharge limits need to be more stringent. Environ Toxicol Chem 2022;41:614–634. © 2021 SETAC

中文翻译：

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南非开普敦福尔斯湾周围海洋环境中的药品和个人护理产品：发生率和风险评估研究

由于人类活动，海洋环境的污染日益严重。海洋生态系统的保护以及捕捞海产品的安全性是当今全球关注的问题。在本研究中，对南非开普敦福尔斯湾近岸海洋环境中不同环境隔间的药品和个人护理产品水平进行了评估。该研究揭示了来自该地点的不同环境样本中存在这些持久性化合物。双氯芬酸是检测到的最主要的化合物，其浓度高于其他药物化合物，并且几乎存在于来自不同地点的所有样品中（海水，3.70-4.18 ng/L；沉积物，92.08-171.89 ng/g 干wt；海洋无脊椎动物，67.67–780.26 ng/g 干重；海藻，101。50–309.11 ng/g 干重）。药物和个人护理产品在不同生物物种中的积累反映了由于人口增长、居民生活方式以及几种相关废水处理不当的污水排放，沿海湾的采样点发生的人为压力不断增加-处理厂。这些污染物的浓度按海洋生物群 > 沉积物 > 海水的顺序排列。污染物对选定的营养水平构成低急性和慢性风险。需要开展公众宣传活动以从源头上减少污染，并且需要更加严格的废水排放限制。药物和个人护理产品在不同生物物种中的积累反映了由于人口增长、居民生活方式以及几种相关废水处理不当的污水排放，沿海湾的采样点发生的人为压力不断增加-处理厂。这些污染物的浓度按海洋生物群 > 沉积物 > 海水的顺序排列。污染物对选定的营养水平构成低急性和慢性风险。需要开展公众宣传活动以从源头上减少污染，并且需要更加严格的废水排放限制。药物和个人护理产品在不同生物物种中的积累反映了由于人口增长、居民生活方式以及几种相关废水处理不当的污水排放，沿海湾的采样点发生的人为压力不断增加-处理厂。这些污染物的浓度按海洋生物群 > 沉积物 > 海水的顺序排列。污染物对选定的营养水平构成低急性和慢性风险。需要开展公众宣传活动以从源头上减少污染，并且需要更加严格的废水排放限制。居民的生活方式以及从几个相关的废水处理厂排放的未经处理的污水。这些污染物的浓度按海洋生物群 > 沉积物 > 海水的顺序排列。污染物对选定的营养水平构成低急性和慢性风险。需要开展公众宣传活动以从源头上减少污染，并且需要更加严格的废水排放限制。居民的生活方式以及从几个相关的废水处理厂排放的未经处理的污水。这些污染物的浓度按海洋生物群 > 沉积物 > 海水的顺序排列。污染物对选定的营养水平构成低急性和慢性风险。需要开展公众宣传活动以从源头上减少污染，并且需要更加严格的废水排放限制。环境毒物化学2022；41：614–634。© 2021 SETAC