Animal studies and explant cultures of human lymphoid tissues do not reliably model human vaccine responses. A remarkable strategy for reassociation of human tonsillar cells in ex vivo culture leads to organoid formation and provides an exciting new tool to probe human humoral immune responses to infection.

中文翻译：

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扁桃体类器官：凝视人类免疫力

动物研究和人类淋巴组织的外植体培养不能可靠地模拟人类疫苗反应。在离体培养中与人扁桃体细胞重结合的非凡策略可导致类器官形成，并提供了令人兴奋的新工具来探测人体对感染的体液免疫反应。