Background: The thiocyanation of indoles is a direct way for carbon-sulfur bond formation to access 3-thiocyanato-indoles. 3-thiocyanato-indoles exhibit potent biological and pharmacological activities and also serve as building blocks to synthesize many biologically active sulfur-containing indole derivatives.

Objective: The aim of this review is to highlight different approaches for the thiocyanation of indoles focusing on its scope and mechanism.

Conclusion: In this review, we have summarized various methods for the thiocyanation of indoles. Selection of new methods for the preparation of 3-thiocyanato-indoles will be done. The mechanistic aspects and significance of the methods are also briefly discussed.

背景：吲哚的硫氰化反应是形成碳硫键以获取 3-硫氰基-吲哚的直接途径。3-硫氰酸根合吲哚表现出强大的生物和药理活性，也可作为合成许多具有生物活性的含硫吲哚衍生物的基石。

目的：本综述的目的是强调吲哚硫氰化的不同方法，重点是其范围和机制。

结论：在这篇综述中，我们总结了吲哚硫氰化的各种方法。将选择制备3-硫氰酸根合吲哚的新方法。还简要讨论了这些方法的机械方面和重要性。