Introduction

Intracranial aneurysms (IAs) are localized dilatations of intracranial arteries due to weaknesses of the endothelial layer. IAs may be treated by flow diverters (FDs), alternatively to stents and coils combination. FD is a method for the treatment of IAs especially for large, wide-necked or fusiform aneurysms. In this case report, we described a 65-year-old woman with IA who were treated by FD.

Case presentation

A 65-year-old woman was diagnosed with a giant aneurysm at the posterior inferior cerebellar artery segment of the left internal carotid artery. Then based on the computed tomography data of this woman, aneurysm vascular stent model was constructed before and after FD, and internal pressure, velocity, wall shear stress (WSS) of aneurysms were determined by CFD analysis. Standard boundary conditions were applied. It was found that a single FD stent and double FD stents decreased the blood flow and WSS of aneurysm. The effect of single FD stent + 30% filling on blood flow was more obvious, but the aneurysm rupture was caused by excessive coil packing. So, a single stent + 10% coil packing rate was the best option for treating aneurysms.

Conclusions

CFD analysis for flow velocity and WSS have protection on aneurysms.

中文翻译：

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分流器治疗颅内动脉瘤的计算流体动力学分析：病例报告

介绍

颅内动脉瘤 (IAs) 是由于内皮层薄弱导致颅内动脉局部扩张。IA 可以通过分流器 (FD) 治疗，替代支架和线圈组合。FD 是一种治疗 IA 的方法，尤其适用于大型、宽颈或梭形动脉瘤。在本病例报告中，我们描述了一名 65 岁患有 IA 的女性，她接受了 FD 治疗。

案例展示

一名 65 岁女性被诊断为左侧颈内动脉小脑后下动脉段巨大动脉瘤。然后根据该女性的CT数据，构建FD前后动脉瘤血管支架模型，通过CFD分析确定动脉瘤的内压、速度、壁剪切应力（WSS）。应用标准边界条件。发现单FD支架和双FD支架降低了动脉瘤的血流量和WSS。单支FD支架 +  30%充填对血流的影响更为明显，但动脉瘤破裂是由于弹簧圈填塞过多所致。因此，单个支架 +  10% 的线圈填充率是治疗动脉瘤的最佳选择。

结论

流速和 WSS 的 CFD 分析对动脉瘤有保护作用。