The association between osteoporosis and periodontal disease (PD) has been revealed by previous studies, but there have been few studies on the association in younger adults. We enrolled a total of 7298 adults aged 40 to 44 who underwent PD screening between 2003 and 2008. Data on quantitative ultrasound for the measurement of bone mineral density (BMD) were collected for the diagnostic criteria of osteopenia and osteoporosis. The Community Periodontal Index (CPI) was measured for defining PD. A multiple logistic regression model was used to assess the effect of low bone mass on the risk of PD. Of 7298 enrollees, 31% had periodontal pockets >3 mm, 36.2% had osteopenia, and 2.1% had osteoporosis. The 39.8% of PD prevalence was high in adults with osteoporosis, followed by 33.3% in osteopenia. A negative association was found between BMD and CPI value (p < 0.0001). Low bone mass was associated with the risk of PD (adjusted OR: 1.13; 95% CI:1.02–1.26) after adjusting the confounding factors, including age, gender, education level, overweight, smoking status, past history of osteoporosis, and diabetes mellitus. An association between BMD and PD among young adults was found. An intervention program for the prevention of PD and osteoporosis could be considered starting in young adults.

中文翻译：

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中年成年人骨矿物质密度与牙周疾病的关系

先前的研究已经揭示了骨质疏松症与牙周疾病（PD）之间的关联，但是很少有关于年轻人的关联的研究。我们纳入了2003年至2008年之间接受PD筛查的7298名40至44岁的成年人。收集了用于骨质疏松和骨质疏松症诊断标准的定量超声数据，以测量骨矿物质密度（BMD）。测量社区牙周指数（CPI）以定义PD。使用多元逻辑回归模型评估低骨量对PD风险的影响。在7298名参与者中，有31％的牙周袋> 3 mm，有36.2％的骨质疏松症，有2.1％的骨质疏松症。成人骨质疏松症的PD患病率高达39.8％，其次是骨质疏松症的33.3％。p < 0.0001）。调整混杂因素，包括年龄，性别，教育水平，超重，吸烟状况，骨质疏松症的既往史和糖尿病后，低骨量与PD的风险相关（校正OR：1.13； 95％CI：1.02-1.26）的。发现年轻人中BMD和PD之间存在关联。可以考虑在年轻人中开始一项预防PD和骨质疏松症的干预计划。