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Combined multi‐band decoupling in biomolecular NMR spectroscopy
Journal of Biomolecular NMR ( IF 2.7 ) Pub Date : 2021-03-22 , DOI: 10.1007/s10858-021-00360-2
Clemens Anklin 1 , R Andrew Byrd 2
Affiliation  

Multi-resonance NMR experiments are powerful analytical and structural tools. Their conceptualization assumes that RF fields may be combined independently to manipulate spin interactions. However, practical implementation can compromise performance. One limitation is the generation of combination bands when two or more RF fields are applied simultaneously within the NMR probe. The combination bands can lead to significant interference with the detection circuitry. A facile approach to combined multi-band decoupling can resolve these problems and increase sensitivity two-fold (or more), by time sharing the application of the individual frequencies rather than time sharing decoupling and data acquisition.



中文翻译:

生物分子核磁共振波谱中的组合多波段解耦

多共振核磁共振实验是强大的分析和结构工具。他们的概念化假设射频场可以独立组合以操纵自旋相互作用。但是,实际实施可能会影响性能。一个限制是在 NMR 探头内同时应用两个或多个 RF 场时会产生组合带。组合频带可能导致对检测电路的显着干扰。通过分时应用各个频率而不是分时去耦和数据采集,组合多频带去耦的简便方法可以解决这些问题并将灵敏度提高两倍(或更多)。

更新日期:2021-03-23
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