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Manifestations of domination: Assessments of social dominance in rodents
Genes, Brain and Behavior ( IF 2.5 ) Pub Date : 2021-03-26 , DOI: 10.1111/gbb.12731
Hannah D Fulenwider 1 , Maya A Caruso 1 , Andrey E Ryabinin 1
Affiliation  

Social hierarchies are ubiquitous features of virtually all animal groups. The varying social ranks of members within these groups have profound effects on both physical and emotional health, with lower-ranked individuals typically being the most adversely affected by their respective ranks. Thus, reliable measures of social dominance in preclinical rodent models are necessary to better understand the effects of an individual's social rank on other behaviors and physiological processes. In this review, we outline the primary methodologies used to assess social dominance in various rodent species: those that are based on analyses of agonistic behaviors, and those that are based on resource competition. In synthesizing this review, we conclude that assays based on resource competition may be better suited to characterize social dominance in a wider variety of rodent species and strains, and in both males and females. Lastly, albeit expectedly, we demonstrate that similarly to many other areas of preclinical research, studies incorporating female subjects are lacking in comparison to those using males. These findings emphasize the need for an increased number of studies assessing social dominance in females to form a more comprehensive understanding of this behavioral phenomenon.

中文翻译:

支配的表现:啮齿类动物社会支配的评估

社会等级制度几乎是所有动物群体的普遍特征。这些群体中成员的不同社会等级对身体和情绪健康都有深远的影响,等级较低的人通常受其各自等级的不利影响最大。因此,为了更好地了解个体社会地位对其他行为和生理过程的影响,有必要在临床前啮齿动物模型中可靠地衡量社会支配地位。在这篇综述中,我们概述了用于评估各种啮齿动物的社会支配地位的主要方法:基于竞争行为分析的方法,以及基于资源竞争的方法。在综合这篇评论时,我们得出结论,基于资源竞争的分析可能更适合描述更广泛的啮齿动物物种和品系以及雄性和雌性啮齿动物的社会支配地位。最后,尽管是意料之中的,我们证明与许多其他临床前研究领域类似,与使用男性的研究相比,缺乏纳入女性受试者的研究。这些发现强调需要更多的研究来评估女性的社会支配地位,以便更全面地了解这种行为现象。
更新日期:2021-03-26
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