The heterocyclic compounds are the building blocks for the synthesis of the different biologically active compounds in the organic chemistry. Heterocyclic compounds have versatile synthetic applicability and biological activity. Pyrazole carboxylic acid derivatives are significant scaffold structures in heterocyclic compounds due to biologic activities such as antimicrobial, anticancer, inflammatory, antidepressant, antifungal anti-tubercular and antiviral, etc. The aim of this mini-review is an overview synthesis of pyrazole carboxylic acid derivatives and their biologic applications. The summarized literature survey presents biological activities of pyrazole carboxylic acid derivatives and their various synthetic methods in detail. This mini-review can be a guide to many scientists in medicinal chemistry.

杂环化合物是有机化学中合成不同生物活性化合物的基础。杂环化合物具有通用的合成适用性和生物活性。吡唑羧酸衍生物是杂环化合物中的重要骨架结构，这归因于其生物活性，例如抗微生物剂，抗癌剂，炎性药物，抗抑郁药，抗真菌抗结核药和抗病毒药等。本综述的目的是概述吡唑羧酸衍生物及其生物学应用。汇总的文献综述详细介绍了吡唑羧酸衍生物的生物活性及其各种合成方法。这份简短的综述可以为许多药物化学科学家提供指南。