Abstract

This study explores different episodic memory domains, namely object, temporal and spatial memory, affected in patients with a clinical diagnosis of single domain amnestic mild cognitive impairment (aMCI). 15 aMCI patients and 25 healthy controls were recruited and tested. Object, spatial, and temporal memory were tested using computerized tasks and again in interactive, real-world tasks. Controls outperformed patients on the object computerized task and showed a trend toward significance for the computerized spatial and temporal tasks, but there was no difference in spatial and temporal memory when using the interactive tasks, indicating the employment of compensatory mechanisms in patients to overcome some of the memory impairments associated with aMCI. These findings highlight that aMCI patients might delay seeking help due to compensatory mechanisms which mask their deficits in real-world situations.

摘要

本研究探讨了在临床诊断为单域遗忘性轻度认知障碍 (aMCI) 的患者中受影响的不同情景记忆域，即对象、时间和空间记忆。招募并测试了 15 名 aMCI 患者和 25 名健康对照。对象、空间和时间记忆使用计算机化任务进行了测试，并再次在交互式真实世界任务中进行了测试。控制在对象计算机化任务上的表现优于患者，并且在计算机化时空任务上表现出显着趋势，但在使用交互任务时时空记忆没有差异，表明患者使用补偿机制来克服一些与 aMCI 相关的记忆障碍。