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Nanoarchitectonics: a New Horizon for Drug Targeting
Journal of Pharmaceutical Innovation ( IF 2.6 ) Pub Date : 2021-03-23 , DOI: 10.1007/s12247-021-09550-9
Tanaji Nandgude , Ankita Kawtikwar

Nanoarchitectonics is an emerging multidisciplinary field that has the potential to offer trailblazing solutions to various challenging therapies by facilitating precise and tailored control of physicochemical properties, morphology, and also the biological effects of nano-sized drugs. In this review, various examples of drug delivery based on the nanoarchitectonic approach are discussed. The article consists of various nanoarchitectured materials like cell-penetrating peptide (CPP), mesoporous substances, layered structural motifs, tumour-triggered targeting mesoporous silica nanoparticle (TTTMSN), DNA hybrid, clay based, fullerene based, and inorganic materials like gold and silver. This new concept is a horizon for drug delivery and can significantly expand the possibilities in this area.



中文翻译:

纳米建筑:药物靶向的新视野

纳米建筑学是一个新兴的多学科领域,它通过促进对纳米化学药物的物理化学性质,形态以及生物学效应的精确和量身定制的控制,有潜力为各种挑战性疗法提供开拓性的解决方案。在这篇综述中,讨论了基于纳米建筑方法的药物递送的各种实例。本文由各种纳米结构材料组成,例如细胞穿透肽(CPP),中孔物质,分层结构图案,肿瘤触发的靶向中孔二氧化硅纳米颗粒(TTTMSN),DNA杂化物,基于粘土,基于富勒烯的无机材料,如金和银。这个新概念是药物输送的视界,并且可以大大扩展该领域的可能性。

更新日期:2021-03-23
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