Owing to their autocatalytic properties, gold nanoparticles (AuNPs) are used in biomedical applications. While their usage in neurodegenerative disease control, diabetes, etc. has been documented, their function is mostly untapped in cardiovascular disease treatment. Hence, in this work is the leading to combine, classify and test cardiomyoblast hypertrophy efficiency of AuNPs. In the case of AuNPs, the Imperata cylindrica extracts (IPC) and gold solution (HAuCl₄) were fabricated with 1:5 volume ratios and were distinguished by specific processes, such as ultraviolet–visible (UV–vis) spectroscopy, scanning electron microscopy (SEM) and high resolution transmission electron microscopy (HRTEM). The radical scavenging of superoxide and hydroxylic AuNPs has been shown to be stronger relative to bulk gold and extracts. In cell line tests, rat cardiomyoblasts H9c2 and 3T3 fluorescence were used in this work. The generation of intracellular superoxide anion was less due to the incubation of greater AuNPs levels. In addition, preliminary findings gave an insight into the role of AuNPs in attenuating cardiomyoblastic induced isoproterenol hypertrophy.

由于其自催化性能，金纳米颗粒（AuNPs）用于生物医学应用。尽管已经证明了它们在神经退行性疾病控制，糖尿病等方面的用途，但是在心血管疾病的治疗中它们的功能大多尚未开发。因此，这项工作是结合，分类和测试AuNPs心肌成纤维细胞肥大效率的先导。就AuNP而言，白茅（Imperata cylindrica）提取物（IPC）和金溶液（HAuCl ₄）以1：5的体积比制造，并通过特定的工艺进行区分，例如紫外可见（UV-vis）光谱，扫描电子显微镜（SEM）和高分辨率透射电子显微镜（HRTEM）。已证明，相对于大量金和提取物，超氧化物和羟基AuNPs的自由基清除作用更强。在细胞系测试中，大鼠心肌细胞H9c2和3T3荧光用于这项工作。细胞内超氧阴离子的产生较少，这是由于孵育了更高的AuNPs水平。此外，初步发现对AuNPs在减轻心肌成纤维细胞引起的异丙肾上腺素肥大中的作用有深入的了解。