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E2F5 Promotes the Malignancy of Ovarian Cancer Via the Regulation of Hippo and Wnt Pathways
Genetic Testing and Molecular Biomarkers ( IF 1.4 ) Pub Date : 2021-03-17 , DOI: 10.1089/gtmb.2020.0166
Shika Hanif Malgundkar 1 , Ikram Burney 2 , Mansour Al Moundhri 2 , Moza Al Kalbani 3 , Ritu Lakhtakia 4 , Aikou Okamoto 5 , Yahya Tamimi 1
Affiliation  

Background:E2F5 is a transcription factor that is overexpressed in the early stages of ovarian cancer and has been suggested as a potential biomarker for early detection. In this study, we aimed to examine the role of E2F5 in invasion and proliferation of ovarian cancer cells.

中文翻译:

E2F5 通过调节 Hippo 和 Wnt 通路促进卵巢癌的恶性程度

背景: E2F5是一种在卵巢癌早期过度表达的转录因子,已被建议作为早期检测的潜在生物标志物。在这项研究中,我们旨在检查E2F5在卵巢癌细胞侵袭和增殖中的作用。
更新日期:2021-03-19
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