Magnetic resonance imaging (MRI) is increasingly used in radiation oncology for target delineation and radiotherapy treatment planning, for example, in patients with gynecological cancers. As a consequence of pelvic radiotherapy, a part of the bowel is irradiated, yielding risk of bowel toxicity. Existing dose-effect models predicting bowel toxicity are inconclusive and bowel motion might be an important confounding factor. The exact motion of the bowel and dosimetric effects of its motion are yet uncharted territories in radiotherapy. In diagnostic radiology methods on the acquisition of dynamic MRI sequences were developed for bowel motility visualization and quantification. Our study aim was to develop an imaging technique based on three-dimensional (3D) cine-MRI to visualize and quantify bowel motion and demonstrate it in a cohort of gynecological cancer patients.

中文翻译：

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用于量化妇科癌症患者排便的 3D 电影-MRI 采集技术和图像分析框架

磁共振成像 (MRI) 越来越多地用于放射肿瘤学，用于目标描绘和放射治疗计划，例如，妇科癌症患者。作为盆腔放疗的结果，部分肠道受到照射，产生肠道毒性风险。现有的预测肠道毒性的剂量效应模型尚无定论，排便可能是一个重要的混杂因素。肠道的精确运动及其运动的剂量学效应在放射治疗中尚属未知领域。在诊断放射学中，获取动态 MRI 序列的方法被开发用于肠道运动的可视化和量化。